95,00  excl. 19% VAT


Z-LR-AMC | Z-Leu-Arg-MCA

3210-v 5 mg | 95.00 EUR

Benzyloxycarbonyl- L-leucyl- L-arginine 4-methylcoumaryl-7-amide

(M.W. 578,66) C30H38N6O6

Synthetic Product (Hydrochloride Form)
A trace of impurity might be detectable by TLC when 100 µg is applied to the plate. The amount of contamination detectable by HPLC is less than 2 %.

Substrate for Cathepsin K / S / V

The Benzyloxycarbonyl-protected Dipeptide Z-Leu-Arg-AMC was carfully manufactured at Peptide Institute and is a widly used fluorogenic substrate for Cathepsine K, S and V. (Z-Leu-Arg-MCA is used in Japan as synonym for Z-Leu-Arg-AMC)


  1. D. Brömme, K. Okamoto, B.B. Wang and S. Biroc, J. Biol. Chem., 271, 2126 (1996)
  2. D. Brömme, Z. Li, M. Barnes and E. Mehler, Biochemistry, 38, 2377 (1999)

For Laboratory use only! Not for Drug Use!