Sarafotoxin B
Sarafotoxin S6b | SRTX-B
(Snake, Atractaspis engaddensis)

4206-s 0.1 mg | 120.00 EUR

Cys – Ser – Cys – Lys – Asp – Met – Thr – Asp – Lys – Glu – Cys – Leu – Tyr – Phe – Cys – His – Gln – Asp – Val – Ile – Trp

Synthetic Product Trifluoracetate Form (disulfide bonds between Cys¹– Cys¹⁵ and Cys³– Cys¹¹)

The purity is guaranteed to be higher than 99% by HPLC

Endothelin Related Peptide | The synthetic peptide Sarafotoxin B (S6b, SRTX-B) manufactured by Peptide Institute Inc. was initially isolated from Snake, Atractaspis engaddensis and shows a very close structural and functional relationship to Endothelin-2 , which can be ordered as well from PeptaNova. The vasoconstictive effects induced by Sarafotoxin S6b seems to be weaker and not as long lasting.

The biological activity of Sarafotoxin S6b is examined by the Division of Pharmacology, Peptide Institute, Inc.

References:

1. PC. Takasaki, N. Tamiya, A. Bdolah, Z. Wollberg and E. Kochva, Toxicon., 26, 543 (1988) (Original; Chem. Structure of Sarafotoxin B)
2. JY. Kloog, I. Ambar, M. Sokolovsky, E. Kochva, Z. Wollberg and A. Bdolah, Science, 242, 268 (1988) (Original; Biochem.)
3. K. Nakajima, S. Kumagaye, H. Nishio, H. Kuroda, T.X. Watanabe, Y. Kobayashi, H. Tamaoki, T. Kimura and S. Sakakibara, J. Cardiovasc. Pharmacol., 13, S8 (1989) (Chem. Synthesis & Biological Activity of Sarafotoxin)
4. T.X. Watanabe, Y. Itahara, K. Nakajima, S. Kumagaye, T. Kimura, and S. Sakakibara, J. Cardiovasc. Pharmacol., 17 (Suppl.7), S5 (1991) (Pharmacology of Sarafotoxin)