Muscarinic Toxin 7
MT7; MTX7; m1-toxin1
(Green Mamba, Dendroaspis angusticeps)

4340-s 0.1 mg | 230.00 EUR

Leu – Thr – Cys – Val – Lys – Ser – Asn – Ser – Ile – Trp – Phe – Pro – Thr – Ser – Glu – Asp – Cys – Pro – Asp – Gly – Gln – Asn – Leu – Cys – Phe – Lys – Arg – Trp – Gln – Tyr – Ile – Ser – Pro – Arg – Met – Tyr – Asp – Phe – Thr – Arg – Gly – Cys – Ala – Ala – Thr – Cys – Pro – Lys – Ala – Glu – Tyr – Arg – Asp – Val – Ile – Asn – Cys – Cys – Gly – Thr – Asp – Lys – Cys – Asn – Lys

Synthetic Product (disulfide bonds between Cys³– Cys²⁴, Cys¹⁷– Cys⁴², Cys⁴⁶– Cys⁵⁷ and Cys⁵⁸– Cys⁶³ )

The purity of muscarinic toxin 7 code 4340-s is guaranteed to be higher than 99% by HPLC

Specific Ligand for Muscarinic Acetylcholine Receptor-1 (M1)

References:

1. A. Adem and E. Karlsson, Life Sci., 60, 1069 (1997) (Original)
2. H. Nishio, Y. Nishiuchi, T. Inui, K.N. Bradley, A.L. Harvey and T. Kimura, Peptide Science 1999, 125 (2000) (S-S Bond)
3. J.M. Carsi and L.T. Potter, Toxicon, 38, 187 (2000) (Original; m1-toxin1)
4. Z. Gu, P. Zhong and Z. Yan, J. Biol. Chem., 278, 17546 (2003) (Pharmacol. Inhibiting of β-Amyloid signaling)