Alpha-Defensin-1 (Human)

Alpha-Defensin-1 (Human)

140,00  excl. 19% VAT

Alpha-Defensin-1 (Human)
α-Defensin-1 | HNP-1 (Human Neutrophil Peptide-1)

4271-s 0.1 mg | 140.00 EUR

Synthetic Product (disulfide bonds between Cys2-Cys30, Cys4-Cys19 and Cys9-Cys29)

Ala – Cys – Tyr – Cys – Arg – Ile – Pro – Ala – Cys – Ile – Ala – Gly – Glu – Arg – Arg – Tyr – Gly – Thr – Cys – Ile – Tyr – Gln – Gly – Arg – Leu – Trp – Ala – Phe – Cys – Cys

(M.W. 3442.0) C150H222N44O38S6

The purity of alpha-Defensin-1 is guaranteed to be higher than 99% by HPLC

HNP-1 (Human) | Alpha-Defensin-1 (Human) is described as enogenous antimicrobial peptide and Chemoattractant for Monocytes. Human Neutrophil Peptide-1 is a potent stimulator of the expression of the genes for different types of collagen and plays a potential part in the biosynthetic and tissue remodeling responses of conjunctival fibroblasts. HNP-1 (Human) | Alpha-Defensin-1 (Human) shows characteristics like an antibiotic against a wide spectrum of infectious agents.
Alpha-Defensin-1 from Peptide Institute is from chemical synthesis and is not made by using recombinant methods.


  1. T. Ganz, M.E. Selstedt, D. Szklarek, S.S.L. Harwig, K. Daher, D.F. Bainton and R.I. Lehrer, J. Clin. Invest., 76, 1427 (1985) (Original description and isolation of alpha-defensin-1)
  2. M.E. Selstedt, S.S.L. Harwig, T. Ganz, J.W. Schilling and R.I. Lehrer, J. Clin. Invest., 76, 1427 (1985) (Structure of HNP-1 (Human Neutrophil Peptide-1))

Links to publications that used our antimicrobial peptide HNP-1:

  1. Community-acquired meticillin-resistant Staphylococcus aureus strain USA300 resists staphylococcal protein A modulation by antibiotics and antimicrobial peptides
  2. Human alpha-defensin-1 protects cells from intoxication with Clostridium perfringens iota toxin

For Laboratory use only! Not for Drug Use!