Ac-YVKD-CHO | Ac-Tyr-Val-Lys-Asp-H (aldehyde)
3166-v 5 mg | 148.00 EUR
Acetyl- L- Tyrosyl- L- Valyl- L- Lysyl- L- Aspartinal
| (M.W. 549.62) | C26H39N5O8 | [147821-01-1] |
Synthetic Product (Trifluoroacetate Form)
Caspase-1 (ICE) Inhibitor – Slow-binding inhibitor, with low selectivity
The vial contains exactly 5.0 mg ( 9.0 µmol ) of the substrate Ac-YVKD-CHO, which has been lyophilized as an amorphous powder from aqueous solution.
Solution: Carefully open the cap. Pour 0.9 ml of DMSO* (analytical grade) into the vial. Close the cap tightly. Shake well until all the contents are dissolved. This procedure furnishes a 10 mM solution of the titled compound. *DMSO: dimethyl sulfoxide
Advice: Do not use an aqueous buffer solution substitute for DMSO. If an aqueous buffer solution is used, this compound may racemize soon. The DMSO solution is stable at -20″C for more than one month if it is protected from moisture and kept in the dark.
References:
- N.A. Thornberry et al, Nature, 356, 368 (1992)
- T.L. Graybill, R.E. Dolle, C.T. Helaszek, R.E. Miller, and M.A. Ator, Int. J. Pept. Protein Res., 44, 173 (1994)
