Ac-YVKD-CHO | Ac-Tyr-Val-Lys-Asp-H (aldehyde)

3166-v 5 mg | 175.00 EUR

Acetyl-L-Tyrosyl-L-Valyl-L-Lysyl-L-Aspartinal

Synthetic Product (Trifluoroacetate Form)

Caspase-1 (ICE) Inhibitor – Slow-binding inhibitor, with low selectivity

The vial contains exactly 5.0 mg ( 9.0 µmol ) of the substrate Ac-YVKD-CHO, which has been lyophilized as an amorphous powder from aqueous solution.
Solution: Carefully open the cap. Pour 0.9 ml of DMSO* (analytical grade) into the vial. Close the cap tightly. Shake well until all the contents are dissolved. This procedure furnishes a 10 mM solution of the titled compound. *DMSO: dimethyl sulfoxide
Advice: Do not use an aqueous buffer solution substitute for DMSO. If an aqueous buffer solution is used, this compound may racemize soon. The DMSO solution is stable at -20″C for more than one month if it is protected from moisture and kept in the dark.

References:

1. N.A. Thornberry et al, Nature, 356, 368 (1992)
2. T.L. Graybill, R.E. Dolle, C.T. Helaszek, R.E. Miller, and M.A. Ator, Int. J. Pept. Protein Res., 44, 173 (1994)

For Laboratory use only! Not for Drug Use!