Ac-DEVD-CHO | Ac-Asp-Glu-Val-Asp-H (aldehyde)
3172-v 5 mg | 148.00 EUR
Acetyl- L-aspartyl- L-glutaminyl- L-threonyl- L-aspart-1-al
(M.W. 502.48) | C20H30N4O11 | [184179-08-6] |
Synthetic Product
Reversible inhibitor for Caspase-3/7/8
The frequently used Caspase 3/7 inhibitors from type DEVD are similar to a short partial sequence of the DNA repair enzyme Poly (ADP- ribose) polymerase. The reversible inhibitor Ac-DEVD-CHO is corresponding to the related and often used AMC substrate Ac-DEVD-AMC code: 3171-v. Both peptides the inhibitor and the substrate are available for prompt delivery ex stock Sandhausen.
References:
- D.W. Nicholson, A. Ali, N.A. Thornberry, J.P. Vaillancourt, C.K. Ding, M. Gallant, Y. Gareau, P.R. Griffin, M. Labelle, Y.A. Lazebnik, N.A. Munday, S.M. Raju, M.E. Smulson, T.-T. Yamin, V.L. Yu and D.K. Miller, Nature, 376, 37 (1995)
- M. Enari, R.V. Talanian, W.W. Wong and S. Nagata, Nature, 380, 723 (1996)
- N.A. Thornberry, T.A. Rano, E.P. Peterson, D.M. Rasper, T. Timkey, M. Garcia-Calvo, V.M. Houtzager, P.A. Nordstrom, S. Roy, J.P. Vaillancourt, K.T. Chapman and D.W. Nicholson, J. Biol. Chem., 272, 17907 (1997)
Links to publications that use our caspase inhibitor Ac-DEVD-CHO | code 3172-v: