Ubiquitin Aldehyde

3207-v 50 µg | 120.00 EUR

Met*- Gln- Ile- Phe- Val- Lys- Thr- Leu- Thr- Gly- Lys- Thr- Ile- Thr- Leu- Glu- Val- Glu- Pro- Ser- Asp- Thr- Ile- Glu- Asn- Val- Lys- Ala- Lys- Ile- Gln- Asp- Lys- Glu- Gly- Ile- Pro- Pro- Asp- Gln- Gln- Arg- Leu- Ile- Phe- Ala- Gly- Lys- Gln- Leu- Glu- Asp- Gly- Arg- Thr- Leu- Ser- Asp- Tyr- Asn- Ile- Gln- Lys- Glu- Ser- Thr- Leu- His- Leu- Val- Leu- Arg- Leu- Arg- Gly- Gly- H (aldehyde)
* Met at position 1 is oxidized to Met(O)

Semisynthetic Product

Inhibitor for Deubiquitinating Enzyme

Ubiquitin aldehyde, a peptide aldehyde of 76 amino acids is produced by a semisynthetic pathway. It is used as very potent and selective inhibitor for Ubiquitin C-terminal hydrolase. Ubiquitin aldehyde is a useful tool to protect ubiquitin-protein conjugates from ubiquitin-dependent degradation.

Shipping | Storage | Stability
Our product Ubiquitin aldehyde will be shipped at room temperature. Information about product specific storage conditions will be found on the vial. Stock solutions should be stored at -20°C. Please avoid repeated freezing and thawing by preparing aliquots.

References:

1. J.R. Shaeffer and R.E. Cohen, Biochemistry, 35, 12893 (1996)
2. F. Melandri, L. Grenier, L. Plamondon, W.P. Huskey, and R.L. Stein, Biochemistry, 35, 12893 (1996)
3. S.H. Baek, K.S. Choi, Y.J. Yoo, J.M. Cho, R.T. Baker, K. Tanaka and C.H. Chung, J. Biol. Chem., 272, 25560 (1997)
4. L.C. Dang, F.D. Melandri and R.L. Stein, Biochemistry, 37, 1868 (1998)