alpha-Conotoxin ImI
α-Conotoxin ImI
(Marine Snail, Conus imperialis)

4311-v 0.5 mg | 410.00 EUR

Synthetic Product (disulfide bonds between Cys²-Cys⁸ and Cys³-Cys¹²)

Gly – Cys – Cys – Ser – Asp – Pro – Arg – Cys – Ala – Trp – Arg – Cys – NH₂

The purity is guaranteed to be higher than 99% by HPLC

Blocker for Nicotinic Acetylcholine Receptor in Central Nervous System

Shipping | Storage | Stability
Our product alpha-Conotoxin ImI will be shipped at room temperature. Information about product specific storage conditions can be found on the vial. Stock solutions should be stored at -20°C. Please avoid repeated freezing and thawing by preparing aliquots.

Important information:
α-Conotoxin IMI can be shipped to autorized end users with own application labs only. We will need a dedicated end user declaration for this item and cannot ship conotoxin to trading companies!

References:

1. J.M. Macintosh, D. Yoshikami, E. Mahe, D.B. Nielsen, J.E. Rivier, W.R. Gray and B.M. Olivera, J. Biol. Chem., 269, 16733 (1994) (Original)
2. D.S. Johnson, J. Martinez, A.B. Elgohyen, S.F. Heinemann and J.M. Macintosh, Mol. Pharmacol., 48, 194 (1995) (Pharmacol)
3. E.F.R. Pereira, M. Alkondon, J.M. Macintosh and E.X. Albuquerque, J. Pharmacol. Exp. Ther., 278, 1472 (1996) (Pharmacol.; Competitive Antagonist)