Ac-Val-Asp-Val-Ala-Asp-AMC | Ac-VDVAD-AMC

Ac-Val-Asp-Val-Ala-Asp-MCA | Ac-VDVAD-MCA

3203-v 5 mg | 125.00 EUR

Acetyl- L-valyl- L-aspartyl- L-valyl- L-alanyl- L-aspartic acid α-(4-methyl- coumaryl- 7-amide)

Synthetic Product
A trace of impurity might be detectable by TLC when 100 µg is applied to the plate. The amount of contamination detectable by HPLC is less than 2 %.

Ac-VDVAD-AMC | Substrate for Caspase-2

The N-terminal acetylated synthetic pentapeptide Ac-Val-Asp-Val-Ala-Asp-AMC (Ac-VDVAD-AMC) is a very useful fluorogenic caspase-2 substrate for apoptosis research. (Ex: 380 nm, EM: 460 nm).

References:

1. R.V. Taranian, C. Quinlan, S. Trautz, M.C.Hackett, J.A. Mankovich, D. Banach, T. Ghayur, K.D. Brady and W.W. Wong, J. Biol. Chem., 272, 9677 (1997)

Links to publications that use our substrate Ac-Asp-Glu-Val-Asp-AMC | code 3171-v:

1. Modulation of Mcl-1 transcription by serum deprivation sensitizes cancer cells to cisplatin

For Laboratory use only! Not for Drug Use!