Lipid IVa

Lipid A 406, LA-14-PP, Precursor Ia

24006-s 0.1 mg | 210.00 EUR

2- Deoxy- 6- O- {2- deoxy- 3- O- [(R)- 3- hydroxytetradecanoyl]- 2- [(R)- 3- hydroxytetradecanoylamino]- β- D- glucopyranosyl}- 3- O- [(R)- 3- hydroxytetradecanoyl]- 2- [(R)- 3- hydroxytetradecanoylamino]- α- D- glucopyranose 1,4′- diphosphate

Synthetic Product (Triethylammonium Form)

Download: PDF-structural formula

Lipid IVa | Biosynthetic Precursor of Lipopolysaccharide

References:

1. M. Imoto, S. Kusumoto, T. Shiba, E.Th. Rietschel, C. Galanos and O. Lüderitz, Tetrahedron Lett., 26, 907 (1985) (Original; Chem. Structure)
2. M. Imoto, H. Yoshimura, T. Shimamoto, N. Sakaguchi, S. Kusumoto and T. Shiba, Bull. Chem. Soc. Jpn., 60, 2205 (1987) (Chem. Synthesis)

Links to publications that use our Lipid IVa | code 24006-s:

1. Lipopolysaccharides with Acylation Defects Potentiate TLR4 Signaling and Shape T Cell Responses