MCD-Peptide
Mast Cell Degranulating Peptide
(Honeybee, Apis mellifera)

4258-v 0.5 mg | 205.00 EUR

Ile – Lys – Cys – Asn – Cys – Lys – Arg – His – Val – Ile – Lys – Pro – His – Ile – Cys – Arg – Lys – Ile – Cys – Gly – Lys – Asn – NH₂

Synthetic Product (disulfide bonds between Cys³– Cys¹⁵ and Cys⁵– Cys¹⁹)

The purity of Mast Cell Degranulating Peptide, article no. 4258-v is guaranteed to be higher than 99% by HPLC

MCD-Peptide | Voltage-Dependent K⁺ Channel Blocker

Mast Cell Degranulating (MCD) Peptid, a 22 amino acid residue peptide amide, was originally isolated from the venom of the honeybee Apis mellifera. MCD Peptide may release histidine from the mast cells and is an interesting tool in the research of allergy and inflammation. MCD-Peptide and Dendrotoxin-I are two ion channel blockers of fast activation and slow inactivation K⁺ channels. The biological activity of Mast Cell Degranulating Peptide is examined by the Division of Pharmacology, Peptide Institute, Inc.

Shipping | Storage | Stability
Our product MCD-Peptide will be shipped at room temperature. Information about product specific storage conditions will be found on the vial. Stock solutions should be stored at -20°C. Please avoid repeated freezing and thawing by preparing aliquots.

References:

1. E. Haberman, Science, 177, 314 (1972) (Review)
2. M.R. Ziai, S. Russek, H.C. Wang, B. Beer and A.J. Blume, J. Pharm. Pharmacol., 42, 457 (1990) (Review)

MCD peptide offered from PeptaNova is distributed through Peptide Institute, Inc. under the license of The Salk Institute.