MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2

MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2

95,00  excl. 19% VAT

MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2

Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2
(7-Methoxycoumarin-4-yl)acetyl- L-arginyl- L-prolyl- L-lysyl- L-prolyl- L-valyl- L-glutamyl- L-norvalyl- L-tryptophyl- L-arginyl- Nε– (2,4-dinitrophenyl)- L-lysine amide

Fluorescence-Quenching Substrate for Matrix Metalloproteinase-3 (Stromelysin 1)

3168-v 1 mg | 95.00 EUR

(7-Methoxycoumarin-4-yl)acetyl- L-arginyl- L-prolyl- L-lysyl- L-prolyl- L-valyl- L-glutamyl- L-norvalyl- L-tryptophyl- L-arginyl- Nε– (2,4-dinitrophenyl)- L-lysine amide

(M.W. 1675.90) C78H110N22O20 [158584-09-9]

Synthetic Product
Purity Grade B: Contamination of less than 4% might be detectable by HPLC

In Europe Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 is often used as synonym for MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2

Stromelysin 1 (MMP-3) hydolized quickly and easily our MOCAc/DNP Fluorescence-Quenching Substrate MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 Article No.: 3168-v (Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2)
Gelatinase B (MMP-9) hydolized this substrate much more slower (kcat/Km= 10100 M⁻¹s⁻¹).
MMP-1 and MMP-2 do not show any hydrolysis activities.

The Fluorescence-Quenching Substrate for Matrix Metalloproteinase-3 Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2, Article no.: 3168-v is available for prompt delivery from our store in Sandhausen, Germany.

References:

  1. H. Nagase, C.G. Fields and G.B. Fields, J. Biol. Chem., 269, 20952 (1994)

Links to publications that use our Fluorescence-Quenching Substrate MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 | code 3168-v:

  1. The behavior of cathepsin D during milk processing and its contribution to bitterness in a model fresh cheese

For Laboratory use only!