Lipid A (Alcaligenes faecalis)
Synthetic Lipid A, Alcaligenes faecalis type

24018-s 0.1 mg | 265.00 EUR

2-[(R)-3-(Decanoyloxy)tetradecanoylamino]-2-deoxy-6-O-(2-deoxy-2-{(R)-3-[(R)-3-hydroxydodecanoyloxy]tetradecanoylamino}-3-O-[(R)-3-hydroxytetradecanoyl]-β-D-glucopyranosyl)-3-O-[(R)-3-hydroxytetradecanoyl]-α-D-glucopyranose 1,4′-bisphosphate
(Triethylammonium Form)

Synthetic Product (Triethylammonium Form)

Lipid A (Alcaligenes faecalis) Active Principle of Low-Toxic Endotoxin

Lipid A (Alcaligenes faecalis) purchased from PeptaNova is made by chemical synthesis and is not isolated from biological sources. No biological hazards must be suspected by using Lipid A, Salmonella type manufactured from Peptide Institute, Inc.

References:

1. Y. Wang, K. Hosomi, A. Shimoyama, K. Yoshii, H. Yamaura, T. Nagatake, T. Nishino, H. Kiyono, K. Fukase and J. Kunisawa, Vaccines, 8, 395 (2020) (Adjuvant activity)
2. K. Yoshii, K. Hosomi, A. Shimoyama, Y. Wang, H. Yamaura, T. Nagatake, H. Suzuki, H. Lan, H. Kiyono, K. Fukase and J. Kunisawa, Microorganisms, 8, 1102 (2020) (Adjuvant activity)
3. A. Shimoyama, F. Di Lorenzo, H. Yamaura, K. Mizote, A. Palmigiano, M.D. Pither, I. Speciale, T. Uto, S. Masui, L. Sturiale, D. Garozzo, K. Hosomi, N. Shibata, K. Kabayama, Y. Fujimoto, A. Silipo, J. Kunisawa, H. Kiyono, A. Molinaro and K. Fukase, Chem. Int. Ed., 60, 10023 (2021) (Chem. Synthesis)