cyclo (Arg-Gly-Asp-D-Phe-Val)
4304-v 0.5 mg | 50.00 EUR
cyclo (Arg-Gly-Asp-D-Phe-Val)
(M.W. 574.63) | C26H38N8O7 | [137813-35-5] |
4304-25 mg | 520.00 EUR
cyclo (Arg-Gly-Asp-D-Phe-Val) · AcOH · 2H2O
(M.W. 574.63) · 60.05 · 36.03 | C26H38N8O7 · CH3COOH · 2H2O |
Synthetic Product
The purity is guaranteed to be higher than 99% by HPLC
cyclo (Arg-Gly-Asp-D-Phe-Val) is a potent Angiogenesis Inhibitor. This cyclopeptide induces apoptosis and regression of distinct human tumor cells.
References:
- P.C. Brooks, A.M.P. Montgomery, M. Rosenfeld, R.A. Reisfeld, T. Hu, G. Klier and D.A. Cheresh, Cell, 79, 1157 (1994) (Original)
- M. Friedlander, C.L. Threesfeld, M. Sugita, M. Fruttiger, M.A. Thomas, S. Chang and D.A. Cheresh, Proc. Natl. Acad. Sci. USA, 93, 9764 (1996) (Pharmacology of cyclo (Arg-Gly-Asp-D-Phe-Val).)