Suc-[Glu⁹, Ala^11,15]-Endothelin-1 (8 – 21)
IRL 1620

4285-v 0.5 mg | 105.00 EUR

Synthetic Product)

Suc – Asp – Glu – Glu – Ala – Val – Tyr – Phe – Ala – His – Leu – Asp – Ile – Ile – Trp

Suc: Succinyl

The purity is guaranteed to be higher than 99% by HPLC

ET_B Receptor Selective Agonist

The biological activity of this peptide is examined by the Division of Pharmacology, Peptide Institute, Inc.

References:

1. M. Takai, I. Umemura, K. Yamasaki, T. Watakabe, Y. Fujitani, K. Oda, Y. Urade, T. Inui, T. Yamamura and T. Okada, Biochem. Biophys. Res. Commun., 184, 953 (1992) (Original)
2. S.S. Shetty, T. Okada, R.L. Webb, D. DelGrande and R.W. Lappe, Biochem. Biophys. Res. Commun., 191, 459 (1993) (Pharmacol.)
3. W.G. Haynes, A.P. Davenport and D.J. Webb, Trends Pharmacol. Sci., 14, 225 (1993) (Report; 3rd Int. Conf. Endothelin.)
4. A.F. James, Y. Urade, R.L. Webb, H. Karaki, I. Umemura, Y. Fujitani, K. Oda, T. Okada, R.W. Lappe and M. Takai, Cardiovasc. Drug Rev., 11, 253 (1993) (Review)

This peptide is distributed under the technical and scientific advices of International Research Laboratories of Novartis Pharma K.K.