β-Sheet Breaker Peptide iAβ5
4358-v 5 mg | 155.00 EUR
Synthetic Product (Trifluoroacetate Form)
H-Leu-Pro-Phe-Phe-Asp-OH
| (M.W. 637.72) | C33H43N5O8 |
The purity is guaranteed to be higher than 99% by HPLC
Inhibitor of Amyloid Deposition
The pentapeptide beta-Sheet Breaker Peptide iAβ5 is known to inhibit amyloidogenesis in rat brain models. It disassembles preformed fibrils and reduces amyloid beta-protein deposition in vivo. beta-Sheet Breaker Peptide may be an interesting tool in finding new therapeutic aspects in Alzheimer’s disease research.
References:
- C. Soto, E.M. Sigurdsson, L. Morelli, R.A. Kumar, E.M. Castano, and B. Frangione, Nat. Med., 4, 822 (1998) (Original; Pharmacol.)
