Neuromedin C
Gastrin Releasing Peptide (18-27, Human)
GRP (18-27) (Human, Porcine, Canine)

4153-v 0.5 mg | 45.00 EUR

Gly – Asn – His – Trp – Ala – Val – Gly – His – Leu – Met – NH₂

4153-25 mg | 495.00 EUR

Gly – Asn – His – Trp – Ala – Val – Gly – His – Leu – Met – NH₂ · 2AcOH · 5H₂O

Synthetic Product

The purity is guaranteed to be higher than 99% by HPLC

The biological activity of this peptide is examined by the Division of Pharmacology, Peptide Institute, Inc.

The decapeptide Neuromedin C was initally isolated from porcine spinal cord and canine intestinal muscle. It is identical with the gastrin-releasing peptide (GRP 18-27) and shows bombesin-like activities as well. Neuromedin-C acts as stimulator of amylase release in the same mannor as GRP-27 but Neuromedin-C was twofold more potent.

For Laboratory use only! Not for Drug Use!

References:

1. K.A. Roth, C.J. Evans, R.G. Lorenz, E. Weber, J.D. Barchas and J.K. Chang, Biochem. Biophys. Res. Commun., 112, 528 (1983) (Original; GRP (18-27))
2. N. Minamino, K. Kangawa, and H. Matsuo, Biochem. Biophys. Res. Commun., 119, 14 (1984) (Original; Porcine Neuromedin C)
3. M.S. Orloff, J.R. Reeve Jr., C.M. Ben-Avram, J.E. Shively and J.H. Walsh, Peptides, 5, 8657 (1984) (Isolation & Seq.; Human Bombesin-like Peptide)
4. J.R. Reeve Jr., H. Walsh, P. Chew, B. Clark, D. Hawke and J.E. Shively, J. Biol. Chem., 258, 5582 (1983) (Isolation & Seq.; Canine Bombesin-like Peptide)