Midkine (Human)

4298-v 50 µg | 255.00 EUR

Lys – Lys – Lys – Asp – Lys – Val – Lys – Lys – Gly – Gly – Pro – Gly – Ser – Glu – Cys – Ala – Glu – Trp – Ala – Trp – Gly – Pro – Cys – Thr – Pro – Ser – Ser – Lys – Asp – Cys – Gly – Val – Gly – Phe – Arg – Glu – Gly – Thr – Cys – Gly – Ala – Gln – Thr – Gln – Arg – Ile – Arg – Cys – Arg – Val – Pro – Cys – Asn – Trp – Lys – Lys – Glu – Phe – Gly – Ala – Asp – Cys – Lys – Tyr – Lys – Phe – Glu – Asn – Trp – Gly – Ala – Cys – Asp – Gly – Gly – Thr – Gly – Thr – Lys – Val – Arg – Gln – Gly – Thr – Leu – Lys – Lys – Ala – Arg – Tyr – Asn – Ala – Gln – Cys – Gln – Glu – Thr – Ile – Arg – Val – Thr – Lys – Pro – Cys – Thr – Pro – Lys – Thr – Lys – Ala – Lys – Ala – Lys – Ala – Lys – Lys – Gly – Lys – Gly – Lys – Asp

Synthetic Product bonds between Cys¹⁵– Cys³⁹, Cys²³– Cys⁴⁸, Cys³⁰– Cys⁵², Cys⁶²– Cys⁹⁴, and Cys⁷²– Cys¹⁰⁴

The purity of Midkine is guaranteed to be higher than 99% by HPLC

Midkine is a non glycosylated protein containing five disulfide bridges. Midkine offered from PeptaNova is manufactured by chemical peptide synthesis and is not from recombinant origin. Therefore our midkine did not contain any residual DNA or artefacts from bacterial proteins.

Heparin-Binding Growth / Differentiation Factor
(Neurotrophic Factor, Neurite Outgrowth-Promoting Factor)
Plasminogen Activator Activity Enhancer

Shipping | Storage | Stability
Our synthetic protein Midkine (Human) will be shipped at room temperature. Information about product specific storage conditions will be found on the vial. Stock solutions should be stored at -20°C. Please avoid repeated freezing and thawing by preparing aliquots.

References:

1. J-i. Tsutsui, K. Uehara, K. Kadomatsu, S. Matsubara and T. Muramatsu, Biochem. Biophys. Res. Commun, 176, 792 (1991) (Original)
2. H. Muramatsu, T. Inui, T. Kimura, S. Sakakibara, X.-j. Song, H. Maruta and T. Muramatsu, Biochem. Biophys. Res. Commun, 203, 1131 (1994) (Pharmacology of Midkine)
3. T. Inui, J. Bódi, S. Kubo, H. Nishio, T. Kimura, S.Kojima, H. Maruta, T. Muramatsu and S. Sakakibara, J. Peptide Sci., 2, 28 (1996) (Chem. Synthesis of Midkine)
4. G.S.P. Yu, J. Hu and H. Nakagawa, Neurosci. Lett., 254, 128 (1998) (Pharmacol.; Inhibition of b-amyloid cytotoxicity)

Midkine is distributed through Peptide Institute, Inc. under the license of Prof. Takeshi Muramatsu. The use for any other purpose than research is strictly prohibited.