Guanylin (Human)

Guanylin (Human)

85,00  excl. 19% VAT

SKU: 4274 Category:

Guanylin (Human)

4274-s 0.1 mg 85.00 EUR
4274 5 x 0.1 mg 345.00 EUR


(M.W. 1458.7) C58H87N15O21S4

Synthetic Product (disulfide bonds between Cys4-Cys12 and Cys7-Cys15)

The purity is guaranteed to be higher than 99% by HPLC

Guanylin is an endogenous intestinal peptide and acts as a common Guanylate Cyclase C Activator. It is part of the regulation of water and electrolyte secretion by intestinal mucosa. Guanylin has structural similarity to bacterial peptides who cause diarrhoea.


  1. R.C. Wiegand, J. Kato, M.D. Huang, K.F. Foc, J.F. Kachur and M.G. Currie, FEBS Lett., 311, 150 (1992) (Original; cDNA)
  2. F.J. de Sauvage, S. Keshav, W.-J. Kuang, N. Gillett, W. Henzel and D.V. Goeddel, Proc. Natl. Acad. Sci. USA, 89, 9089 (1992) (Original; cDNA)
  3. M. Kuhn, M. Raida, K. Adermann, P. Schulz-Knappe, R. Gerzer, J.-M. Heim, and W.-G. Forssmann, FEBS Lett., 318, 205 (1993) (Guanylin |Circulating Form)
  4. O. Hill, M. Kuhn, H.-D. Zucht, Y. Cetin, H. Kulaksiz, K. Adermann, G. Klock, G. Rechkemmer, W.-G. Forssmann and H.-J. Maegert, Proc. Natl. Acad. Sci. USA., 92, 2046 (1995) (Immunohistochemistry of Guanylin)