Fmoc-His(MBom)
2328 1 g | 145.00 EUR
2328 5 g | 585.00 EUR
Nα-9-Fluorenylmethoxycarbonyl-Nπ-4-methoxybenzyloxymethyl-L-histidine
(M.W. 527.57) | C30H29N3O6 | 1327338-56-6 |
Synthetic Product
New histidine derivative to minimize racemisation risk
The 4-methoxybenzyloxymethyl (MBom) group at the Nπ-position of histidine is explicitly designed for conventional and microwave assisted Fmoc-SPPS. Fmoc-His(MBom) is a useful Fmoc-derivative to suppress the racemization during the coupling process of the His residue.
References:
- H. Hibino, and Y. Nishiuchi, Tetrahedron Lett., 52, 4947(2011)
- H. Hibino, Y. Miki, and Y. Nishiuchi, J. Pept. Sci., 18, 763(2012)
- K. Sakamoto, K. Sato, A. Shigenaga, K. Tsuji, S. Tsuda, H. Hibino, Y. Nishiuchi and A. Otaka, J. Org. Chem., 77, 6948(2012)