Exendin (9-39)

Exendin (9-39)

285,00  excl. 19% VAT

SKU: 4526-v Category:

Exendin (9-39)
(Lizard, Heloderma horridum)

4526-v 0.5 mg | 285.00 EUR

Asp – Leu – Ser – Lys – Gln – Met – Glu – Glu – Glu – Ala – Val – Arg – Leu – Phe – Ile – Glu – Trp – Leu – Lys – Asn – Gly – Gly – Pro – Ser – Ser – Gly – Ala – Pro – Pro – Pro – Ser – NH2

(M.W. 3369.8) C149H234N40O47S

Synthetic Product

The purity is guaranteed to be higher than 98% by HPLC

GLP-1 Receptor Antagonist

Exendin-3 (9-39) amide, Avexitide is described as an antagonist of glucagon-like peptide 1 (GLP-1) receptors.

Our chemically synthesized peptide Exendin (9-39) will be shipped at room temperature. Long term storage is recomended in a freezer at – 18 degrees.

References:

  1. J.-P. Raufman, L. Singh and J. Eng, J. Biol. Chem, 266, 2897 (1991) (Original)
  2. R. Göke, H.-C. Fehmann, T. Linn, H. Schmidt, M. Krause, J. Eng and B. Göke, J. Biol. Chem, 268, 19650 (1993) (Validation as GLP-1 Receptor Antagonist)
  3. M.D. Turton, D. O’Shea, I. Gunn, S.A. Beak, C.M.B. Edwards, K. Meeran, S.J. Choi, G.M. Taylor, M.M. Heath, P.D. Lambert, J.P.H. Wilding, D.M. Smith, M.A. Ghatei, J. Herbert and S.R. Bloom, Nature, 379, 69 (1996)
  4. L.S. Gasbjerg, E.J. Bari, M. Christensen and F.K. Knop, Diabetes. Obes. Metab, 23, 2419 (2021) (Review)

For Laboratory use only! Not for Drug Use!