Des-Acyl Ghrelin (Human)
Des-n-Octanoyl Ghrelin (Human)
4436-s 0.1 mg | 105.00 EUR
Gly – Ser – Ser – Phe – Leu – Ser – Pro – Glu – His – Gln – Arg – Val – Gln – Gln – Arg – Lys – Glu – Ser – Lys – Lys – Pro – Pro – Ala – Lys – Leu – Gln – Pro – Arg
| (M.W. 3244.7) | C141H235N47O41 |
Synthetic Product (Trifluoracetate Form)
The purity of Des-Acyl Ghrelin (Human) is guaranteed to be higher than 99% by HPLC
Des-Octanoylated Ghrelin with Distinct Effect on Food Intake
The fatty acid acylation of ghrelin seems to be essential for the strong GH-releasing activity. The Non-acylated form Des-n-Octanoyl Ghrelin does not bind to the ghrelin receptor and did not induce growth hormone release. Des-Acyl Ghrelin shows inotropic effects in papillary muscle and cardioprotective activity.
References:
- M. Kojima, H. Hosoda, Y. Date, M. Nakazato, H. Matsuo and K. Kangawa, Nature, 402, 656 (1999) (Original)
The peptide Des-n-Octanoyl Ghrelin (Human) is distributed through Peptide Institute, Inc. under the license of Dr. K. Kangawa
