ω-Conotoxin GVIA
omega-Conotoxin GVIA
(Marine Snail, Conus geographus)

4161-v 0.5 mg | 525.00 EUR

Synthetic Product (disulfide bonds between Cys¹-Cys¹⁶, Cys⁸-Cys¹⁹ and Cys¹⁵-Cys²⁶)

Cys – Lys – Ser – Hyp – Gly – Ser – Ser – Cys – Ser – Hyp – Thr – Ser – Tyr – Asn – Cys – Cys – Arg – Ser – Cys – Asn – Hyp – Tyr – Thr – Lys – Arg – Cys – Tyr – NH₂

The purity is guaranteed to be higher than 99% by HPLC

N-type Ca²⁺ Channel Blocker

The biological activity of our peptide toxin omega-Conotoxin GVIA is examined by the Division of Pharmacology, Peptide Institute, Inc.

Important information:
ω-Conotoxin GVIA can be shipped to autorized end users with own application labs only. We will need a dedicated end user declaration for this item and cannot ship conotoxin to trading companies!

References:

1. B.M. Olivera, J.K.McIntosh, L.J. Cruz, F.A. Luque, and W.R. Gray, Biochemistry, 23, 5087 (1984) (Original)
2. Y. Nishiuchi, K.Y. Kumagaye, Y. Noda, T.X. Watanabe and S. Sakakibara, Biopolymers, 25, S61 (1986) (Chem. Synthesis and S-S Bond)

Links to publications that use our peptide ω-Conotoxin GVIA | code 4161-v:

1. Altered synaptic transmission at olfactory and vomeronasal nerve terminals in mice lacking N-type calcium channel Cav2.