Big Gastrin I (Human)
4183-s 0.1 mg | 115.00 EUR
4183-v 0.5 mg | 445.00 EUR
Pyr – Leu – Gly – Pro – Gln – Gly – Pro – Pro – His – Leu – Val – Ala – Asp – Pro – Ser – Lys – Lys – Gln – Gly – Pro – Trp – Leu – Glu – Glu – Glu – Glu – Glu – Ala – Tyr – Gly – Trp – Met – Asp – Phe – NH2
| (M.W. 3849.2) | C176H251N43O53S | [60675-77-6] |
Synthetic Product (Ammonium Form) | The purity is guaranteed to be higher than 99% by HPLC
Big-Gastrin I, a 36 mer polypeptide, is produced in vivo together with other gastrin peptides from the precursor peptide, progastrin. Big Gastrin is a stimulator for the parietal cells of the stomach and for the production of pancreatic enzymes.
References:
- A.M. Choudhury, G.W. Kenner, S. Moore, K.L. Ramachandran, W.D. Thorpe, R. Ramage, G.J. Dockray, R.A. Gregory, L. Hood and M. Hunkapiller, Hoppe-Seyler’s Z. Physiol. Chem., 361, 1719 (1980) (Original with Chem. Synthesis of Big Gastrin)
- Handbook of Experimental Pharmacology,Secretin, Cholecystokinin, Pancreozymin and Gastrin,(J.E. Jorpes and V. Mutt, eds.), Springer-Verlag, Berlin Vol.: 34, (1973) (Gastrin; Review)
