Amyloid beta-Protein (Human, 1 – 42)

Amyloid β-Protein (Human, 1 – 42)

4349-v 0.5 mg | 265.00 EUR

Synthetic Product (Trifluoroacetate Form)

Asp – Ala – Glu – Phe – Arg – His – Asp – Ser – Gly – Tyr – Glu – Val – His – His – Gln – Lys – Leu – Val – Phe – Phe – Ala – Glu – Asp – Val – Gly – Ser – Asn – Lys – Gly – Ala – Ile – Ile – Gly – Leu – Met – Val – Gly – Gly – Val – Val -Ile – Ala

The purity is guaranteed to be higher than 95% by HPLC

Amyloid beta-Protein (Human, 1 – 42) is the major plaque component which is found in brain and cerebrospinal fluid of Alzheimer Disease patients

References:

1. D. Goldgaber, M.I. Lerman, O.W. McBride, U. Saffiotti and D.C. Gajdusek, Science, 235, 877 (1987) (Original; cDNA)
2. A.E. Roher, J.D. Lowenson, S. Clarke, A.S. Woods, R.J. Cotter, E. Gowing and M.J. Ball, Proc. Natl. Acad. Sci. USA, 90, 10836 (1993) (Pathophysiology)
3. N. Suzuki, T.T. Cheung, X.-D. Cai, A. Okada, L. Otvos Jr., C. Eckman, T.E. Golde and S.G. Younkin, Science, 264, 1336 (1994) (Pathophysiology)
4. M. Citron, T.S. Diehl, G. Gordon, A.L. Biere, P. Seubert and D.J. Selkoe, Proc. Natl. Acad. Sci. USA, 93, 13170 (1996) (Biosynthesis)