Amylin (Human)
IAPP (Islet Amyloid Polypeptide) | DAP (Diabetes-Associated Peptide)
4219-v 0.5 mg | 295.00 EUR/Vial
Synthetic Product (Disulfide bonds between Cys2-Cys7)
Lys – Cys – Asn – Thr – Ala – Thr – Cys – Ala – Thr – Gln – Arg – Leu – Ala – Asn – Phe – Leu – Val – His – Ser – Ser – Asn – Asn – Phe – Gly – Ala – Ile – Leu – Ser – Ser – Thr – Asn – Val – Gly – Ser – Asn – Thr – Tyr – NH2
| (M.W. 3903.3) | C165H261N51O55S2 | [122384-88-7] |
The purity of Amylin (Human) is guaranteed to be higher than 97% by HPLC
Amylin (Human) is a 37 mer polypeptide with two disulfid bridges, which shows suplementary activities to insulin. This peptide hormone called Islet amyloid polypeptide (IAPP) or alternatively Amylin was secreted by pancreatic β-cells like insulin or glucagon depending to food intake.
References:
- P. Westermark, C. Wernstedt, E. Wilander, D.W. Hayden, T.D. O´Brian and K.H. Johnson, Proc. Natl. Acad. Sci. USA, 84, 3881 (1987) (Original)
- G.J.S. Cooper, A.C. Willis, A. Clark, R.C. Turner, R.B. Sim and K.B.M. Reid, Proc. Natl. Acad. Sci. USA, 84, 8628 (1987) (Original; Complete Sequence of Amylin)
- A. Clark, G.J.S. Cooper, C.E. Lewis, F.J. Morris, A.C. Willis, K.B.M. Reid and R.C. Turner, Lancet, 2, 231 (1987) (Pathologics)
